When the first atomic bomb was detonated in July of 1945, for the first time, man had the means to totally destroy himself. The Bible says that if Jesus was to delay His return to earth, man would completely annihilate himself.
“Behold, the LORD maketh the earth empty, and maketh it waste, and turneth it upside down, and scattereth abroad the inhabitants there of. Therefore hath the curse devoured the earth, and they that dwell therein are desolate: therefore the inhabitants of the earth are burned, and few men left.” (Isa 24:1,6) (Rev 8:7) (Rev 9:16-18)